5-bromo-6-chloro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one

5-bromo-6-chloro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one - Names and Identifiers

Name	5-Bromo-6-chloro-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
Synonyms	5-BroMo-6-chloro-7-aza-2-oxindole 5-Bromo-6-chloro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one 5-bromo-6-chloro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one 5-Bromo-6-chloro-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one 5-Bromo-6-chloro-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one 2H-Pyrrolo[2,3-b]pyridin-2-one, 5-broMo-6-chloro-1,3-dihydro-
CAS	297757-11-0
InChI	InChI=1S/C7H4BrClN2O/c8-4-1-3-2-5(12)10-7(3)11-6(4)9/h1H,2H2,(H,10,11,12)

5-bromo-6-chloro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one - Physico-chemical Properties

Molecular Formula	C7H4BrClN2O
Molar Mass	247.48
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

5-bromo-6-chloro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one - Introduction

5-Bromo-6-chloro-1, 3-dihydro-2h-pyrirolo [2,3-b]pyridin-2-one is an organic compound with the formula C9H5BrClN2O and a molecular weight of 256.51G/mole. The following is a detailed description of the nature, use, preparation and safety information:

Nature:
-Appearance: 5-Bromo-6-chloro-1, 3-dihydro-2h-pyrirolo [2,3-b]pyridin-2-one is white crystal or crystalline powder.
-Melting point: Its melting point range is 160-162 ° C.
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM), insoluble in water.

Use:
-drug research: 5-Bromo-6-chloro-1, 3-dihydro-2h-pyrirolo [2,3-b]pyridin-2-one is a potential drug molecular skeleton, it is widely used in the field of pharmaceutical research to synthesize new pharmaceutical compounds.
-Organic synthesis: It can also be used as a starting material in organic synthesis and used to synthesize other compounds.

Method:
The preparation method of 5-Bromo-6-chloro-1, 3-dihydro-2h-pyrirolo [2,3-b]pyridin-2-one is more complicated, and it is generally synthesized by multi-step reaction. The general synthetic route involves chlorination and bromination of isoindoles, followed by substitution reactions at the 5-and 6-positions, and finally structural identification and purification of the product.

Safety Information:
- 5-Bromo-6-chloro-1, 3-dihydro-2h-pyrirolo [2,3-b]pyridin-2-one has limited toxicity data and no definitive toxicity report has been reported. However, like any organic compound, it can be toxic and dangerous.
-Appropriate safety measures need to be taken during testing or use, including wearing appropriate protective equipment (e. G. Gloves, glasses, laboratory clothing) and ensuring good ventilation.
-For the use of any chemical, please refer to the specific chemical Safety Data Sheet (MSDS) or consult a professional for more detailed safety information.

Last Update：2024-04-09 20:45:29